Introduction: Heterotopic ossification is defined as the ectopic extrasceletal bonetissue formation in the periarticular muscles and soft tissues due to prolonged immobilization after spinal cord and traumatic brain injuries (neurogenic heterotopic ossification). Case report: We describe the case of a 23-year-old apparently healthy man who suffered from a severe SARS-CoV-2 infection. He required mechanical ventillation ECMO treatment and immobilization of almost 3 months in an intensive Covid-19 care unit. He later experienced an extensive and progressive bilateral and multiplex heterotopic ossification affecting around the hips, the shoulders, the elbows and the knees. This postCOVID-19 late complication was discovered at the beginning of his early rehabilitation. The diagnosis was based on the physical examination, laboratory test results (alkaline phosphatase and inflammatory markers) and the two directional X-rays. The young patient significantly narrowed range of passive joint movement was greatly improved during rehabilitation treatment, he become walkable with assistive devices. Conclusions: Among the late complications of postCOVID-19, the literature reports joint pain in about one-fifth of the cases. Against the background of these, the development of heterotopic ossification should be considered, which requires early special rehabilitation therapy and sometimes orthopedic surgical treatment as well.